NAR Molecular Biology Database Collection entry number 0790

Database Description

The Transporter Classification Database (TCDB) is a curated, relational database containing sequence, classification, structural, functional and evolutionary information about transport systems from a variety of living organisms. TCDB is a repository for information compiled from more than 10,000 references, encompassing approximately 3,000 representative transporters and putative transporters, classified into over 400 families. The Transporter Classification (TC) system is an International Union of Biochemistry and Molecular Biology (IUBMB) approved system of nomenclature for transport protein classification. The web interface provides several different methods for accessing the data, including step-by-step access to hierarchical classification, direct search by sequence or TC number and full-text searching. The TCDB website also offers several tools specifically designed for analyzing the unique characteristics of transport proteins.

Acknowledgements

Work in Saier laboratory is supported by NIH grants 2R01 AI14176 from The National Institute of Allergy and Infectious Diseases and 9RO1 GM55434 from the National Institute of General Medical Sciences, as well as by the M. H. Saier, Sr., Memorial Research Fund.

References

1. Saier, M.H., Jr. (2000) A functional-phylogenetic classification system for transmembrane solute transporters. Microbiol. Mol. Biol. Rev., 64, 354-411.

2. Busch, W. and M.H. Saier, Jr. (2002) The Transporter Classification (TC) System, 2002. CRC Crit. Rev. Biochem. Mol. Biol. 37, 287-337.

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