SCWRL

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Contents 1 Database Description 2 Authors 3 External Links 4 Contact Email 5 Paper

[edit] Database Description

SCWRL is a program for adding sidechains to a protein backbone.

SCWRL3.0 is based on an algorithm based on graph theory that solves the combinatorial problem in side-chain prediction more rapidly than many other available program.

It depends on a backbone-dependent rotamer library. The library provides lists of chi1-chi2-chi3-chi4 values and their relative probabilities for residues at given phi-psi values, and explores these conformations to minimize sidechain-backbone clashes and sidechain-sidechain clashes.

[edit] Authors

Canutescu A.

Dunbrack R.

[edit] External Links

SCWRL 3.0 can be downloaded for installation at http://dunbrack.fccc.edu/SCWRL3.php

An online server for SCWRL 2.8 is available at http://bioserv.cbs.cnrs.fr/HTML_BIO/frame_scwrl.html

[edit] Contact Email

No link

[edit] Paper

A. A. Canutescu, A. A. Shelenkov, and R. L. Dunbrack, Jr. A graph theory algorithm for protein side-chain prediction. Protein Science 12, 2001-2014 (2003)