Rfam

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Text from the NAR 2007 Database Issue (Database Summaries) by permission of Oxford University Press.

Rfam is NAR Database No. 382.

Contents

Database Description

Rfam is a collection of multiple sequence alignments and covariance models representing non-coding RNA families. Rfam is available on the web in the UK at http://www.sanger.ac.uk/Software/Rfam/ and in the US at http://rfam.wustl.edu/. These websites allow the user to search a query sequence against a library of covariance models, and view multiple sequence alignments and family annotation. The database can also be downloaded in flatfile form and searched locally using the INFERNAL package (http://infernal.wustl.edu/). The first release of Rfam (1.0) contains 25 families, which annotate over 50000 non-coding RNA genes in the taxonomic divisions of the EMBL nucleotide database.

Authors

Griffiths-Jones, S.1, Bateman, A.1, Marshall, M.1, Khanna, A.2, Eddy, S.R.2

1Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SA, UK
2Howard Hughes Medical Institute and Department of Genetics, Washington University School of Medicine, St. Louis, MO 63110, USA


External Links

Contact Email



Text from the NAR 2007 Web Server Issue (Web Server Summaries) by permission of Oxford University Press.

Rfam is NAR Web Server Collection No. 657.

Web Server Description

Database of structure-annotated multiple sequence alignments, covariance models and family annotation for a number of non-coding RNA families.

External Links

Contact Email

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See also; Rfam in Wikipedia.


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