PhytAMP
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PhytAMP a database dedicated to plant antimicrobial peptides
Contents |
[edit] Database Description
Plants produce small cysteine-rich antimicrobial peptides as an innate defense against pathogens. Based on amino acid sequence homology, these peptides were classified mostly as α-defensins, thionins, lipid transfer proteins (LTPs), cyclotides, snakins and hevein-like. Although many antimicrobial plant peptides are now well characterized, much information is still missing or is unavailable to potential users.
The compilation of such information in one centralized resource such as a database would therefore facilitate the study of the potential these peptide structures represent, for example as alternatives in response to increasing antibiotic resistance or for increasing plant resistance to pathogens by genetic engineering.
To achieve this goal, a new database was developed, PhytAMP, which contains valuable information on antimicrobial plant peptides, including taxonomic, microbiological and physicochemical data. Information is very easy to extract from this database and allows rapid prediction of structure / function relationships and target organisms and hence better exploitation of plant peptide biological activities in both the pharmaceutical and agricultural sectors. PhytAMP may be accessed free of charge at http://phytamp.pfba-lab.org.
[edit] Authors
- Hammami Riadh, PhD
- Ben Hamida Jeannette, PhD
- Vergoten Gérard, PhD
- Fliss Ismail, PhD
[edit] Contact Email
[edit] References
- Hammami R, Ben Hamida J, Vergoten G, Fliss I. Phytamp: a database dedicated to plant antimicrobial peptides. PMID 18836196 , doi:10.1093/nar/gkn655
[edit] External Links
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