Fly-FISH

From MetaBase

Fly-Fish is A searchable web resource documenting mRNA expression and localization dynamics.

Contents 1 Database Description 2 Related Databases 3 Authors 3.1 Contact Email 4 External Links 5 Publications

[edit] Database Description

Image:Fly-FISH.logo.jpg

This database documents the expression patterns of Drosophila mRNAs at the subcellular level during early embryogenesis. A high-resolution, high-throughput fluorescence detection method is used to detect expressed mRNAs. The overall findings and implications of the work performed thus far is summarized in Lecuyer et al (2007). The data can be accessed by searching the localization categories, searching for specific genes or browsing the list of tested genes.

The database will serve as an invaluable tool for dissecting localization mechanisms and for predicting gene functions and interactions.

[edit] Related Databases

• FlyBase

[edit] Authors

• Lécuyer E
• Yoshida H
• Parthasarathy N
• Alm C
• Babak T
• Cerovina T
• Hughes TR
• Tomancak P
• Krause HM

[edit] Contact Email

Eric Lecuyer

[edit] External Links

• Fly-FISH homepage
• BDGP in situ database
• Flybase
• FISH protocol
• Krause lab

[edit] Publications

• Lécuyer E, Yoshida H, Parthasarathy N, Alm C, Babak T, Cerovina T, Hughes TR, Tomancak P, Krause HM. 2007. Global analysis of mRNA localization reveals a prominent role in organizing cellular architecture and function. Cell. 131(1):174-87. PubMed
• Tomancak P, Beaton A, Weiszmann R, Kwan E, Shu S, Lewis SE, Richards S, Ashburner M, Hartenstein V, Celniker SE, Rubin GM. 2002. Systematic determination of patterns of gene expression during Drosophila embryogenesis.

Genome Biol. 3(12):RESEARCH0088. PubMed